anaesthesianow

Friday, January 13, 2006

BUPIVACAINE VS. ROPIVACAINE FOR SPINAL ANESTHESIA FOR C-SECTION
Craig H. Leicht, MD MPH and Ivan A Velickovic, MD


The dosage and efficacy of spinal ropivacaine for Cesarean delivery has not been well defined. Hyperbaric ropivacaine (18mg) appears to provide adequate analgesia for cesarean section . However, the use of low-dose isobaric ropivacaine for spinal anesthesia for Cesarean section has not been previously reported. The purpose of this study was to evaluate the efficacy and safety of spinal anesthesia with 1% isobaric ropivacaine and to compare the results obtained to 0.75% hyperbaric bupivacaine controls.
This on-going analysis received Institutional Review Board approval for the review of medical records of all Cesarean section patients from the previous one-year period (2001).
Patients were stratified into two groups: isobaric ropivacaine 1%, and hyperbaric bupivacaine 0.75%. Data collected included: spinal anesthetic dose, duration of procedure, adjuncts to the spinal anesthetic, intra-operative adjunctive analgesics, episodes of hypotension requiring treatment, side effects requiring treatment and duration of post-op analgesia.
Demographic data were similar in both groups. Onset time, adjunctive intraoperative analgesia, intraoperative ephedrine use, time to first request for postoperative analgesia, total postoperative analgesic requirement and side effects requiring treatment, did not differ between the two groups.
Canadian Journal of Anesthesia 49:A59 (2002)

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